Description
NoMetfor
Description
Food supplement containing carcinogen, anti-glycating, de-glycating and anti-aging.
Inhibition of the synergy between glycation and oxidation reactions.
Stopping scavenging propagators (glucose, glyoxal, etc.).
Inhibition of lipid peroxidation.
Chelation of metal ions.
Anti-aging skin treatment.
Use:
-internal medicine: metabolic syndrome, diabetic complications, obesity;
-gynecology: polycystic ovary syndrome (PCOS);
-dermatology: antiaging (publication on Carcinina at the 24th World Congress of Dermatology-Milan 2019);
-Ophthalmology: cataracts, retinal degeneration.
Property
Carcinine is more stable than carnosine, it is not attacked by the enzyme carnosinase, nor converted into histidine. It is quickly assimilated, resistant to gastric pH, skin, serum and tissue peptidases. It has a longer duration in the body, allowing to improve its effectiveness against glycation.
Ingredients
Glycoless (carcinine dihydrochloride), Lithotame (Lithothamnion calcareum Areschoug) thallus powder, magnesium stearate, chromium picolinate, vegetable gelatin capsule (E171).
Nutritional characteristics
How to use
1 capsule to be taken in the morning on an empty stomach.
Conservation
Store at a temperature not exceeding +25°C.
Validity with intact packaging: 36 months.
Format
Pack of 15 capsules.
Code NOM
Bibliography
1. "The role of carcinine treatment on glycolipid imbalance of overweight and obese women", Palmieri B., Pepe V., Simas Law, Granzoti R., Novak B., Wolpe Re, Zilbert B., Yamaguchi Em, Vadalà M., Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic.
2. "Carcinine supplementation and its implication on human blood sugar, glycated hemoglobin, insulin, frutosamine and lipid profile in women with overweight and obesity: a double-controlled randomized clinical trial controlled by placebo." Simas, L.A.W.; Granzoti; r.; Novak, b; wolpe, rE; Zilbert, b.; Yamaguchi, eM
3. "L-Carnosine(-alanyl-L-histidine) and carcinine F-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities", Mark A. Babizhayev, Marie-Christine Seguin, Jean Gueynej, Rima P. Evstigneeva, Elena A. Ageyeva and Galina A. Zheltukhinai, Moscow Helmholtz Research Institute of Eye Diseases, Russia, and IM.V. Lomonosov Institute of Fine Chemical Technology, Russia, Exsymol SAM, Monaco, Principality of Monaco.
4. “Carcinine Has 4-Hydroxynonenal Scavenging Property and Neuroprotective Effect in Mouse Retina,” Lea D. Marchette, Huaiwen Wang, Feng Li, Mark A. Babizhayev, Anne Kasus-Jacobi, Departments of Ophthalmology, Molecular Biology Proteomics Facility, and Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
5. “Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells”, Studies on the Cornea and Lens, pp 131-144, Anne Kasus-Jacobi (Department of Pharmaceutical Sciences and Oklahoma Center for Neuroscience), Vibudhuta Awasthi (Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences), Mark A. Babizhayev (Innovative Vision Products Inc., Moscow, Russia), H. Anne Pereira (Departments of Pharmaceutical Sciences, Pathology, and Cell Biology and Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, USA).
6. “Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine”, Research Article ,International Journal of Clinical Dermatology & Research (IJCDR), Babizhayev Mark A. (Innovative Vision Products, Inc).
7. “Advanced Glycation End-Products and Their Receptor-Mediated Roles: Inflammation and Oxidative Stress,” Parisa Younessi, Ali Yoonessi, Iran J Med Sci, September 2011; Vol 36 No. 3.
8. A. Pegova, "Comp. Biochem. Physiol.", vol. 127, (2000). pp. 443-446.
Food supplement containing carcinogen, anti-glycating, de-glycating and anti-aging.
Inhibition of the synergy between glycation and oxidation reactions.
Stopping scavenging propagators (glucose, glyoxal, etc.).
Inhibition of lipid peroxidation.
Chelation of metal ions.
Anti-aging skin treatment.
Use:
-internal medicine: metabolic syndrome, diabetic complications, obesity;
-gynecology: polycystic ovary syndrome (PCOS);
-dermatology: antiaging (publication on Carcinina at the 24th World Congress of Dermatology-Milan 2019);
-Ophthalmology: cataracts, retinal degeneration.
Property
Carcinine is more stable than carnosine, it is not attacked by the enzyme carnosinase, nor converted into histidine. It is quickly assimilated, resistant to gastric pH, skin, serum and tissue peptidases. It has a longer duration in the body, allowing to improve its effectiveness against glycation.
Ingredients
Glycoless (carcinine dihydrochloride), Lithotame (Lithothamnion calcareum Areschoug) thallus powder, magnesium stearate, chromium picolinate, vegetable gelatin capsule (E171).
Nutritional characteristics
| Average values per 1 capsule | |
|---|---|
| Glycoless | 200 mg |
| Lithotamus | 200 mg |
| Magnesium stearate | 2 mg |
| Chromium Picolinate | 1.66 mg |
How to use
1 capsule to be taken in the morning on an empty stomach.
Conservation
Store at a temperature not exceeding +25°C.
Validity with intact packaging: 36 months.
Format
Pack of 15 capsules.
Code NOM
Bibliography
1. "The role of carcinine treatment on glycolipid imbalance of overweight and obese women", Palmieri B., Pepe V., Simas Law, Granzoti R., Novak B., Wolpe Re, Zilbert B., Yamaguchi Em, Vadalà M., Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic.
2. "Carcinine supplementation and its implication on human blood sugar, glycated hemoglobin, insulin, frutosamine and lipid profile in women with overweight and obesity: a double-controlled randomized clinical trial controlled by placebo." Simas, L.A.W.; Granzoti; r.; Novak, b; wolpe, rE; Zilbert, b.; Yamaguchi, eM
3. "L-Carnosine(-alanyl-L-histidine) and carcinine F-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities", Mark A. Babizhayev, Marie-Christine Seguin, Jean Gueynej, Rima P. Evstigneeva, Elena A. Ageyeva and Galina A. Zheltukhinai, Moscow Helmholtz Research Institute of Eye Diseases, Russia, and IM.V. Lomonosov Institute of Fine Chemical Technology, Russia, Exsymol SAM, Monaco, Principality of Monaco.
4. “Carcinine Has 4-Hydroxynonenal Scavenging Property and Neuroprotective Effect in Mouse Retina,” Lea D. Marchette, Huaiwen Wang, Feng Li, Mark A. Babizhayev, Anne Kasus-Jacobi, Departments of Ophthalmology, Molecular Biology Proteomics Facility, and Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
5. “Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells”, Studies on the Cornea and Lens, pp 131-144, Anne Kasus-Jacobi (Department of Pharmaceutical Sciences and Oklahoma Center for Neuroscience), Vibudhuta Awasthi (Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences), Mark A. Babizhayev (Innovative Vision Products Inc., Moscow, Russia), H. Anne Pereira (Departments of Pharmaceutical Sciences, Pathology, and Cell Biology and Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, USA).
6. “Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine”, Research Article ,International Journal of Clinical Dermatology & Research (IJCDR), Babizhayev Mark A. (Innovative Vision Products, Inc).
7. “Advanced Glycation End-Products and Their Receptor-Mediated Roles: Inflammation and Oxidative Stress,” Parisa Younessi, Ali Yoonessi, Iran J Med Sci, September 2011; Vol 36 No. 3.
8. A. Pegova, "Comp. Biochem. Physiol.", vol. 127, (2000). pp. 443-446.
