Description
Hepatoguna
Description
Nutraceutical food supplement, with Neorland liver freeze-dried, choline and green tea, thanks to its trophic activity on the liver parenchyma, antioxidant and detoxifying, it finds application as a food support to support liver function.
Ingredients
Bulking agent: microcrystalline cellulose (cellulose gel); freeze-dried pork liver, choline bitartrate; anti-caking agents: fatty acids, silicon dioxide, cross-linked sodium carboxymethylcellulose; green tea (Camellia sinensis L. Kuntze, leaves) dry extract tit. 40% in epigallocatechin gallate (EGCG); anti-caking agents: polyvinylpolypyrrolidone, magnesium salts of fatty acids; coating agent: ethylcellulose; colouring: iron oxide; anti-caking agent: talc; coating agent: caranuba wax.
Nutritional characteristics
How to use
Take 1 swallowable tablet 2 times a day; swallow the tablet with water. It is recommended to take it for at least 2 consecutive months.
Warnings
Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Not recommended during pregnancy. Supplements should not be considered as a substitute for a varied, balanced diet and a healthy lifestyle.
Conservation
Store the product in a cool, dry place, away from light and heat sources. The expiry date refers to the product correctly stored, in an intact package.
Format
Pack of 32 swallowable tablets of 1.13 g.
Net weight: 36.16 g.
Bibliography
1. Ferroni O, Tassinari R et al. Epatoguna. - Neorland® pork liver freeze-dried is a source of well-preserved and biologically active exosomes on human stem cells. La Med. Biol., 2019/1; 3-9.
2. Fukuda Y et Al. “Effect of liver hydrolysate on hepatic proliferation in regenerating rat liver” Nihon Yakurigaku Zasshi. 1999 Oct;114(4):233-8.
3. Nishikawa T., Bell A., Locker J., et al. Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest. 2015 Mar 16.
4. Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. - Cell. 2007
5. Christ B. et Al. “Implication of hepatic stem cells in functional liver repopulation”; Cytometry Part A .83A: 90,102; 2013
6. Herrera MB. et Al. “Human liver stem cell derived microvesicles accelerate hepatic regeneration in hepatectomized rats”; J.Cell.Mol.Med.Vol 14, n.6B,2010 pp.1605-16189
7. Eirin et Al. “MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells” Gene 551 (2014) 55-64
8. Peng D. et Al. “The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence” Molecular Medicine Reports 7: 836-842; 2013
9. Fatemeh Momen-Heravi et Al. “Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS” www.nature.com/scientificreports May 2015
10. Corbin KD, Abdelmalek MF, Spencer MD, et Al. “Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis.” FASEB J. 2013 [Epub ahead of print]. fj.12-219097.
11. Bose M., Lambert JD, Ju J, Reuhl KR, Shapses SA, et Al. (2008) “The major green tea polyphenol, (2)- epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.” J Nutr.; 138: 1677 - 1683.
Nutraceutical food supplement, with Neorland liver freeze-dried, choline and green tea, thanks to its trophic activity on the liver parenchyma, antioxidant and detoxifying, it finds application as a food support to support liver function.
Ingredients
Bulking agent: microcrystalline cellulose (cellulose gel); freeze-dried pork liver, choline bitartrate; anti-caking agents: fatty acids, silicon dioxide, cross-linked sodium carboxymethylcellulose; green tea (Camellia sinensis L. Kuntze, leaves) dry extract tit. 40% in epigallocatechin gallate (EGCG); anti-caking agents: polyvinylpolypyrrolidone, magnesium salts of fatty acids; coating agent: ethylcellulose; colouring: iron oxide; anti-caking agent: talc; coating agent: caranuba wax.
Nutritional characteristics
| Average values | per 100 g | for 2 tablets |
| Energy | 1.263 kJ 306.3 kcal |
28.44 kJ 6.89 kcal |
| Fats of which saturated |
14.3 g 12.64 g 4.2 g |
0.32 g 0.28 g |
| Carbohydrates of which sugars |
1.4 g 0.3 g |
0.03 g 0.01 g |
| Proteins | 23 g | 0.52 g |
| Salt | 0.63 g | 0.01 g |
| Freeze-dried liver | 26.67 g | 600 mg |
| Choline | 7.33 g | 165 mg |
| Green tea dry extract of which EGCG |
1.78 g 0.71 g |
40 mg 16 mg |
How to use
Take 1 swallowable tablet 2 times a day; swallow the tablet with water. It is recommended to take it for at least 2 consecutive months.
Warnings
Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Not recommended during pregnancy. Supplements should not be considered as a substitute for a varied, balanced diet and a healthy lifestyle.
Conservation
Store the product in a cool, dry place, away from light and heat sources. The expiry date refers to the product correctly stored, in an intact package.
Format
Pack of 32 swallowable tablets of 1.13 g.
Net weight: 36.16 g.
Bibliography
1. Ferroni O, Tassinari R et al. Epatoguna. - Neorland® pork liver freeze-dried is a source of well-preserved and biologically active exosomes on human stem cells. La Med. Biol., 2019/1; 3-9.
2. Fukuda Y et Al. “Effect of liver hydrolysate on hepatic proliferation in regenerating rat liver” Nihon Yakurigaku Zasshi. 1999 Oct;114(4):233-8.
3. Nishikawa T., Bell A., Locker J., et al. Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest. 2015 Mar 16.
4. Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. - Cell. 2007
5. Christ B. et Al. “Implication of hepatic stem cells in functional liver repopulation”; Cytometry Part A .83A: 90,102; 2013
6. Herrera MB. et Al. “Human liver stem cell derived microvesicles accelerate hepatic regeneration in hepatectomized rats”; J.Cell.Mol.Med.Vol 14, n.6B,2010 pp.1605-16189
7. Eirin et Al. “MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells” Gene 551 (2014) 55-64
8. Peng D. et Al. “The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence” Molecular Medicine Reports 7: 836-842; 2013
9. Fatemeh Momen-Heravi et Al. “Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS” www.nature.com/scientificreports May 2015
10. Corbin KD, Abdelmalek MF, Spencer MD, et Al. “Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis.” FASEB J. 2013 [Epub ahead of print]. fj.12-219097.
11. Bose M., Lambert JD, Ju J, Reuhl KR, Shapses SA, et Al. (2008) “The major green tea polyphenol, (2)- epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.” J Nutr.; 138: 1677 - 1683.
