Description
Z-Yal
CE Medical Device.Wetting and lubricating ophthalmic solution based on 0.2% sodium hyaluronic acid.
Hyaluronic acid, thanks to its chemical-physical properties, adheres perfectly to the corneal surface and thus allows for a profitable hydration and lubrication. Hyaluronic acid is of biotechnological origin and has a high molecular weight, which gives it a high adhesion power and a long time of contact with the cornea. It represents the ideal remedy in case of dryness due to various factors such as stress, dust, smoke, prolonged exposure to solar rays, continuous work at video terminals, use of contact lenses.
Composition
Sodium hyaluronate 0.2%; sodium phosphate monobasic monohydrate; sodium phosphate dibasic dodecahydrate; sodium chloride; EDTA disodium bihydrate; WFI water.
Instructions for use
Apply light pressure to the body of the single-dose vial.
Apply 1-2 drops per eye.
You can repeat the operation several times a day as needed.
Warnings
The product is for external ophthalmic use only.
Avoid touching the eye with the tip of the single-dose vial.
Do not use in case of known incompatibility with any component of the preparation.
Do not use the product after the expiry date indicated on the package.
The product must be used within 12 hours of first opening the vial.
Do not dispose of the vial in the environment after use.
Do not store above 25°C.
Keep the preparation out of the reach of children.
Format
20 single-dose vials of 0.5 ml.
Cod. 570.
Bibliography
- Aragonan P. Hyaluronan in the treatment of ocular surface disorders. In Chemistry and Biology of Hyaluronan. HG. Gorg and C. A. Hales (editors). Elsevier ed., 2004:529-551.
- Snlbson GR, Greaves JL, Soper ND, Prjdal JI, wilson CG, Bran AJ. Precorneal residence time of sodium hyaluronate solutions studied by quantitative gamma scintigraphy. Eye. 1990;4:594-602.
- Shimmura S, Ono M, Shinozaki K, Toda i, Takamura E, Mashima Y, Tsubota K. Sodium hyaluronate eyedrops in the treatments of dry eye. Br J Ophthalmol. 1995;79(11):1007-1011.
- Aragona P, Micali A, Paladino G, Ferrari F, Puzzolo D. Effects of tear substitute on conjunctival epithelium of mice. Ophthalmic Res. 2007;39(5):265-75. Epub 2007 Sep.12. PubMed PMID: 17851267.
- Milazzo G, Papa V, Aragona P, Russa S, Russa P, Di Bella A. Efficacy of sodium hyaluronate eye drops of different osmolarities in the symptomatic treatment of dry eye patients. Adv Exp Med Biol. 2002;506(Pt B):1233 -5. PubMed PMID: 12 614058.
- Aragon P, Di Stefano G, Ferrare F, Spinella R, Stila A. Sodium Hyaluronate eye drops of different osmolarity for the treatment of dry eye in Slogren's syndrome patients. Br J Ophthalmol. 2002Aug;86(8):879-84. PubMed PMID: 12140209;PubMed Central PMCID: PMC1771217.
- Aragon P, Papa V, Micali A, Santocomo M, Milazzo G. Long term treatment with sodium hyaluronate-containing artificial tears reduces ocular surface clamage in patients with dry eye. Br J Ophthalmol. 2002feb;82(2):181-4. PubMed PMID: 11815344; PubMed Central PMCID: PMC1771021.
- Papa V, Aragona P, Russa S, Di Bella A, Russa P, Milazzo G. Comparison of hypotonic and isotonic solutions containing sodium hyaluronate on the symptomatic treatment of dry eye patients. Ophthalmology. 2001 Mar Apr;215(2):124-7. PubMed PMID: 11244343.
