Description
Mekin Duo
Description
Mekin Duo contains a microencapsulated source of patented all-trans-MK-7 vitamin K2 (K2VITAL), obtained through a special process that, compared to the common fermentation process, guarantees greater requirements in terms of stability and purity. Thanks to this process, pure 7-trans menaquinone is obtained. This stereoisomerism is very important as it is the only one that ensures correct interaction with enzymes at the level of the cell membrane, guaranteeing the desired biological effect. Vitamin K2 in the form of menaquinone-7, promotes the incorporation of calcium into the bone matrix through the activation of osteocalcin, preventing calcium deposition in soft tissues and arteries.
Ingredients
Magnesium bisglycinate; outer shell: hydroxypropyl methylcellulose; vitamin K2 (menaquinone-7), vitamin B2 (riboflavin), stabilizers: calcium phosphates; anti-caking agents: silicon dioxide, magnesium salts of fatty acids.
Gluten- free and naturally lactose -free.
Nutritional characteristics
How to use
Take one capsule daily after your main meal.
However, it is advisable to seek the advice of your doctor.
Warnings
Supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Do not take in case of hypersensitivity or allergies to one or more components. For pregnant and breastfeeding women it is recommended to seek medical advice.
Conservation
Store in a cool, dry place, at a temperature not exceeding 25°-30°C, away from light and/or heat sources. The minimum shelf life refers to the product correctly stored in its intact packaging.
Validity with intact packaging: 36 months.
Format
Pack of 30 vegetal capsules of 500 mg.
Net weight: 15 g.
Bibliography
LJ Schurgers, C. Vermeer (2000) Determination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrations Haemostasis 30 298-307
P. Szulc, MC Chapuy, PJ Meunier, PD Delmas (1993) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women J Clin Invest 91(4) 1769- 1774.
MHJ Knapen, NE Drummen, E. Smit, C. Vermeer, E. Theuwissen (2013) Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women Osteoporosis Int 24(9) 2499-2507.
K. Pucaj, H. Rasmussen, M. Moller, T. Preston (2011) Safety and toxicological evaluation of a synthetic vitamin K2, menaquinone-7 Toxicol Mech Methods 21(7) 520-532.
E. Theuwissen, EC Cranenburg, MH Knapen et al (2012) Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects Br J Nutr 31 1-6.
Mekin Duo contains a microencapsulated source of patented all-trans-MK-7 vitamin K2 (K2VITAL), obtained through a special process that, compared to the common fermentation process, guarantees greater requirements in terms of stability and purity. Thanks to this process, pure 7-trans menaquinone is obtained. This stereoisomerism is very important as it is the only one that ensures correct interaction with enzymes at the level of the cell membrane, guaranteeing the desired biological effect. Vitamin K2 in the form of menaquinone-7, promotes the incorporation of calcium into the bone matrix through the activation of osteocalcin, preventing calcium deposition in soft tissues and arteries.
Ingredients
Magnesium bisglycinate; outer shell: hydroxypropyl methylcellulose; vitamin K2 (menaquinone-7), vitamin B2 (riboflavin), stabilizers: calcium phosphates; anti-caking agents: silicon dioxide, magnesium salts of fatty acids.
Gluten- free and naturally lactose -free.
Nutritional characteristics
| Average values per daily dose (1 capsule) | |
|---|---|
| Vitamin K2 (Menaquinone) | 110 mcg (113% NRV*) |
| Vitamin B2 | 1.2 mg (80% NRV*) |
| Magnesium | 56.25 mg (15% NRV*) |
How to use
Take one capsule daily after your main meal.
However, it is advisable to seek the advice of your doctor.
Warnings
Supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Do not take in case of hypersensitivity or allergies to one or more components. For pregnant and breastfeeding women it is recommended to seek medical advice.
Conservation
Store in a cool, dry place, at a temperature not exceeding 25°-30°C, away from light and/or heat sources. The minimum shelf life refers to the product correctly stored in its intact packaging.
Validity with intact packaging: 36 months.
Format
Pack of 30 vegetal capsules of 500 mg.
Net weight: 15 g.
Bibliography
LJ Schurgers, C. Vermeer (2000) Determination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrations Haemostasis 30 298-307
P. Szulc, MC Chapuy, PJ Meunier, PD Delmas (1993) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women J Clin Invest 91(4) 1769- 1774.
MHJ Knapen, NE Drummen, E. Smit, C. Vermeer, E. Theuwissen (2013) Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women Osteoporosis Int 24(9) 2499-2507.
K. Pucaj, H. Rasmussen, M. Moller, T. Preston (2011) Safety and toxicological evaluation of a synthetic vitamin K2, menaquinone-7 Toxicol Mech Methods 21(7) 520-532.
E. Theuwissen, EC Cranenburg, MH Knapen et al (2012) Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects Br J Nutr 31 1-6.
