NeoBorocillina Tosse is a powerful sedative and antiseptic for dry cough and protects the mouth and throat from pathogenic germs.
The combination of dextrometrophan hydrobromide and 2,4 dichlorobenzyl alcohol provides rapid and symptomatic action for effective cough treatment. Contains safe ingredients such as ammonium glycyrrhizinate and compressible sugar.
How to use
Adults and children over 12 years: slowly dissolve one lozenge in the mouth every 2-3 hours, up to a maximum of 8 lozenges per day.
Do not exceed the recommended doses.
Warnings
Contraindicated in the following cases:
Hypersensitivity to the active substances or to any of the excipients.
Bronchial asthma, COPD, pneumonia, breathing difficulties, respiratory depression, cardiovascular disease, hypertension, hyperthyroidism, diabetes, glaucoma, prostatic hypertrophy, gastrointestinal and urogenital tract stenosis, epilepsy, severe liver disease.
Do not administer to children under 12 years of age.
Do not use concurrently or within two weeks of treatment with MAO inhibitor antidepressant drugs.
Pregnancy, especially in the first trimester, breastfeeding.
In case of irritating cough with a significant production of mucus (e.g. in patients with diseases such as bronchiectasis and cystic fibrosis) or in patients with neurological diseases associated with a marked reduction in the cough reflex (such as stroke, Parkinson's disease and dementia), treatment with Neo Borocillina Tosse pastilles as a cough suppressant should be administered with particular caution and only on medical advice after a careful risk-benefit assessment.
There is limited information on the use of dextromethorphan in patients with impaired hepatic or renal function. Therefore, Neo Borocillina Tosse pastilles should be administered with caution in such patients, especially in patients with severe impairment.
Dextromethorphan is metabolised by hepatic cytochrome P450 2D6. The activity of this enzyme is genetically determined. Approximately 10% of the population is a slow metaboliser of CYP2D6. Exaggerated and/or prolonged effects of dextromethorphan may occur in poor metabolisers and patients with concomitant use of CYP2D6 inhibitors. Therefore, caution is required in patients who are poor metabolisers of CYP2D6 or who use CYP2D6 inhibitors.
Due to the potential release of histamine, the use of Neo Borocillina Tosse pastilles should be avoided in cases of mastocytosis.
A chronic cough can be an early symptom of asthma and therefore Neo Borocillina Tosse Pastilles is not indicated for the suppression of chronic cough, particularly in children.
Neo Borocillina Tosse pastilles should be used with caution in patients taking serotonergic drugs (other than MAO inhibitor drugs), such as selective serotonin reuptake inhibitors (SSRIs) (e.g. fluoxetine, paroxetine) or tricyclic antidepressant drugs.
The use, especially if prolonged, of products for topical use can give rise to sensitization phenomena. In this case it is necessary to interrupt the treatment and consult the doctor for the purpose of establishing any appropriate therapy.
After 5-7 days of treatment, without appreciable results, consult your doctor.
Important information about some of the excipients
Contains 1.386 g of sucrose (sugar) per tablet. To be taken into consideration in people with diabetes mellitus.
Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.
The product contains aspartame, a source of phenylalanine.
It is not recommended to drink alcohol during therapy.
Dextromethorphan may be mildly addictive. With prolonged use (e.g. exceeding the recommended treatment period), patients may develop tolerance to the drug, as well as mental and physical dependence.
Cases of abuse of dextromethorphan have been reported. Particular caution is recommended with adolescents and young adults, as well as with patients with a history of drug or psychoactive substance abuse.
Patients with a tendency to abuse or dependence should take Neo Borocillina Tosse for short periods and under strict medical supervision.
